The course covers the topics the following chapters: Relevance and principles of Biostatistics with application in Medicine and Biology, descriptive statistics, sampling and sampling distributions, estimation of parameters, probability and probability distribution with emphasis on the normal. It also focuses on tests of hypotheses for one or two means and one or two proportions, measures of association between two continuous variables (correlation and regression) ,two discrete variables (chi-square) and non-parametric tests commonly used in medicine and biology